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The TREAT Longevity DietTM is the Oregon Longevity Project’s synthesis of the traditional Mediterranean diet combined with time-restricted eating. The Mediterranean diet is well known
Ever wonder if different body types respond differently to exercise training? In simplistic terms, humans come in 3 basic body types: Endomorphs (round types with
Inhibition of mTOR Signaling in Parkinson’s Disease Prevents l-DOPA–Induced Dyskinesia Emanuela Santini1, Myriam Heiman Paul Greengard, Emmanuel Valjent, and Gilberto Fisone. Science Signaling 21 Jul 2009: Vol. 2, Issue 80, pp.
Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice Cellular senescence is characterized by an irreversible cell cycle arrest and a pro-inflammatory senescence-associated secretory
The use of any substance derived from a living source to treat or prevent disease is often referred to as a “biologic treatment,” which is
Metabolomics are advanced laboratory tests that give us insight into your metabolic phenotype. The first pillar of Oregon Longevity Project is a deep look into
Joint pain can involve every aspect of our lives – walking, climbing steps, playing sports, working – and even sleeping. And even though it worsens
We define Time Restricted Eating (TRE) as consuming all of our daily calories within a 7-8 hour period of time, and consuming no calories for
Immune senescence is a predictable consequence of aging, and is responsible for many of the diseases of aging, including an increase in mortality from common
Senolytics are drugs and other therapeutics that kill senescent zombie cells and activate autophagy, the natural mechanism whereby we clear senescent cells from our bodies.
Autophagy is the natural, regulated mechanism of the cell that responds to senescence through the removal of unnecessary or dysfunctional cells, aka Zombie cells, and
At least a billion years ago, all eukaryotes (organisms made up of cells that possess a membrane-bound nucleus holding genetic material as well as membrane-bound
What is the Epigenetic Clock? The epigenetic clock is a scientifically validated and reliable measurement of specific genes and the presence or absence of methylations
How did zombie cells enter into our discussion of longevity and anti-aging science at my 70th birthday dinner? We were 4 generations, ranging in age from
